{"product_id":"activelle-1-0-5mg","title":"Activelle (1+0.5)mg","description":"\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eActivelle (1+0.5)mg\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e is a prescription-strength \u003cb\u003econtinuous combined Hormone Replacement Therapy (HRT)\u003c\/b\u003e. It is specifically formulated for postmenopausal women who still have an intact uterus (womb) and are at least one year past their last natural menstrual period.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e \u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eEach film-coated oral tablet combines two primary active hormones:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-list: l0 level1 lfo1; tab-stops: list 36.0pt;\"\u003e\n\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eEstradiol (1 mg):\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e A synthetic form of estrogen that replaces the natural estrogen your body stops producing after menopause. \u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-list: l0 level1 lfo1; tab-stops: list 36.0pt;\"\u003e\n\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eNorethisterone Acetate (0.5 mg):\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e A synthetic form of progestin (progesterone) added specifically to protect the uterine lining.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; margin-left: 36.0pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eThis comprehensive guide details the indications, administration protocols, potential side effects, and vital boxed warnings associated with \u003cb\u003eActivelle 1mg\/0.5mg\u003c\/b\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e \u003c\/p\u003e\n\u003cdiv class=\"MsoNormal\" align=\"center\" style=\"margin-bottom: .0001pt; text-align: center; line-height: normal;\"\u003e\u003chr size=\"2\" width=\"100%\" align=\"center\"\u003e\u003c\/div\u003e\n\u003cp class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-outline-level: 3;\"\u003e\u003cb\u003e\u003cspan style=\"font-size: 13.5pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eKey Medical Uses and Benefits of Activelle (1+0.5)mg\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eAs women undergo menopause, declining estrogen levels can cause a wide range of disruptive physical and physiological symptoms. \u003cb\u003eActivelle (1+0.5)mg\u003c\/b\u003e helps restore hormonal balance to provide targeted therapeutic relief:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-list: l1 level1 lfo2; tab-stops: list 36.0pt;\"\u003e\n\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eRelief of Vasomotor Symptoms:\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e Rapidly diminishes the frequency and severity of moderate-to-severe \u003cb\u003ehot flashes, night sweats\u003c\/b\u003e, and sudden flushing caused by menopausal transitions.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-list: l1 level1 lfo2; tab-stops: list 36.0pt;\"\u003e\n\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eManagement of Vulvovaginal Atrophy:\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e Treats the structural thinning, drying, and inflammation of the vaginal walls. This helps reduce symptoms like vaginal dryness, irritation, and painful intercourse (dyspareunia).\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-list: l1 level1 lfo2; tab-stops: list 36.0pt;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e \u003cb\u003ePrevention of Postmenopausal Osteoporosis:\u003c\/b\u003e For women at high risk of bone fractures who cannot take other non-hormonal medications, Activelle helps maintain bone mineral density and stop postmenopausal bone loss.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; margin-left: 36.0pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"MsoNormal\" align=\"center\" style=\"margin-bottom: .0001pt; text-align: center; line-height: normal;\"\u003e\u003chr size=\"2\" width=\"100%\" align=\"center\"\u003e\u003c\/div\u003e\n\u003cp class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-outline-level: 3;\"\u003e\u003cb\u003e\u003cspan style=\"font-size: 13.5pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eWhy the Progestin Component is Essential\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eTaking estrogen alone (unopposed estrogen) causes the lining of the uterus to thicken, which heavily increases the risk of developing endometrial cancer. The \u003cb\u003e0.5 mg of Norethisterone Acetate\u003c\/b\u003e in Activelle acts as a safeguard. It stops the uterine lining from overgrowing, keeping it thin and substantially lowering the risk of \u003cb\u003eendometrial hyperplasia\u003c\/b\u003e and uterine cancer.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003ci\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eNote: Women who have had a total hysterectomy (uterine removal surgery) do not need progestin and should generally take estrogen-only therapies instead.\u003c\/span\u003e\u003c\/i\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"MsoNormal\" align=\"center\" style=\"margin-bottom: .0001pt; text-align: center; line-height: normal;\"\u003e\u003chr size=\"2\" width=\"100%\" align=\"center\"\u003e\u003c\/div\u003e\n\u003cp class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-outline-level: 3;\"\u003e\u003cb\u003e\u003cspan style=\"font-size: 13.5pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eHow to Take Activelle (1+0.5)mg\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eFor optimal safety and therapeutic absorption, always take this medication strictly according to the guidelines outlined by your healthcare provider:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-list: l2 level1 lfo3; tab-stops: list 36.0pt;\"\u003e\n\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eDaily Administration:\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e Take exactly \u003cb\u003eone tablet daily\u003c\/b\u003e. Because it is a \u003ci\u003econtinuous combined\u003c\/i\u003e therapy, you take the tablets sequentially without any pill-free breaks between packs.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; margin-left: 36.0pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e \u003cb\u003eConsistency:\u003c\/b\u003e Swallow the tablet whole with a glass of water at the same time every day. It can be taken safely with or without food.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; margin-left: 36.0pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e \u003cb\u003eMissed Doses:\u003c\/b\u003e If you forget a dose, take it as soon as you remember within 12 hours. If more than 12 hours have passed, skip the missed tablet entirely and take your next regular dose the following day. \u003cb\u003eDo not take a double dose\u003c\/b\u003e to compensate, as this can trigger breakthrough bleeding or spotting.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; margin-left: 36.0pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"MsoNormal\" align=\"center\" style=\"margin-bottom: .0001pt; text-align: center; line-height: normal;\"\u003e\u003chr size=\"2\" width=\"100%\" align=\"center\"\u003e\u003c\/div\u003e\n\u003cp class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-outline-level: 3;\"\u003e\u003cb\u003e\u003cspan style=\"font-size: 13.5pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003ePotential Side Effects of Activelle (1+0.5)mg\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eWhile your body acclimates to the hormone replacement regimen, you may experience minor systemic adjustments. Most common side effects fade over the first few months of starting treatment.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-outline-level: 4;\"\u003e\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eCommon, Mild Side Effects:\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-list: l3 level1 lfo4; tab-stops: list 36.0pt;\"\u003e\n\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eHeadaches\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e (reported in up to 22% of users) or dizziness. \u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-list: l3 level1 lfo4; tab-stops: list 36.0pt;\"\u003e\n\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eBreast pain, tenderness\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e, or temporary breast swelling. \u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-list: l3 level1 lfo4; tab-stops: list 36.0pt;\"\u003e\n\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eIrregular vaginal spotting or breakthrough bleeding\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e (common during the first 3 to 6 months of therapy). \u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-list: l3 level1 lfo4; tab-stops: list 36.0pt;\"\u003e\n\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eNausea, bloating, abdominal cramps\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e, or minor weight fluctuations. \u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-list: l3 level1 lfo4; tab-stops: list 36.0pt;\"\u003e\n\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eMood shifts\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e, sleep disturbances, or mild fatigue.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; margin-left: 36.0pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-outline-level: 4;\"\u003e\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eSerious Side Effects (Seek Emergency Medical Care Immediately):\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-list: l5 level1 lfo5; tab-stops: list 36.0pt;\"\u003e\n\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eSigns of a Blood Clot (DVT\/PE):\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e Sudden swelling, localized redness, heat, or severe pain in one leg; unexplained coughing, sudden chest pain, or difficulty breathing.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-list: l5 level1 lfo5; tab-stops: list 36.0pt;\"\u003e\n\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eSigns of a Stroke or Heart Attack:\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e Sudden, severe headaches; loss of physical coordination; blurred vision; slurred speech; or crushing chest pain radiating to the jaw or arm.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; margin-left: 36.0pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-list: l5 level1 lfo5; tab-stops: list 36.0pt;\"\u003e\n\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eSigns of Liver Problems:\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e Yellowing of the skin or eyes (jaundice), dark urine, or severe upper stomach pain.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; margin-left: 36.0pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-list: l5 level1 lfo5; tab-stops: list 36.0pt;\"\u003e\n\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eBreast Changes:\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e A newly developed lump in the breast or underarm, or unusual nipple discharge.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; margin-left: 36.0pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"MsoNormal\" align=\"center\" style=\"margin-bottom: .0001pt; text-align: center; line-height: normal;\"\u003e\u003chr size=\"2\" width=\"100%\" align=\"center\"\u003e\u003c\/div\u003e\n\u003cp class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-outline-level: 3;\"\u003e\u003cb\u003e\u003cspan style=\"font-size: 13.5pt; font-family: 'Segoe UI Symbol',sans-serif; mso-fareast-font-family: 'Times New Roman'; mso-bidi-font-family: 'Segoe UI Symbol';\"\u003e⚠️\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan style=\"font-size: 13.5pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e Boxed Warnings and Contraindications\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eSystemic Hormone Replacement Therapies carry specific regulatory warnings regarding long-term cardiovascular and oncological risks. Activelle should be prescribed at the \u003cb\u003elowest effective dose for the shortest duration necessary\u003c\/b\u003e to meet clinical goals.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eDo not take Activelle (1+0.5)mg if you have a history of or active diagnosis for any of the following conditions:\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003col start=\"1\" type=\"1\"\u003e\n\u003cli class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-list: l4 level1 lfo6; tab-stops: list 36.0pt;\"\u003e\n\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eUndiagnosed abnormal vaginal bleeding\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e. \u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-list: l4 level1 lfo6; tab-stops: list 36.0pt;\"\u003e\n\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eKnown, suspected, or historical breast cancer\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e or estrogen-dependent tumors. \u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-list: l4 level1 lfo6; tab-stops: list 36.0pt;\"\u003e\n\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eActive or historical blood clots\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e (Deep Vein Thrombosis or Pulmonary Embolism). \u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-list: l4 level1 lfo6; tab-stops: list 36.0pt;\"\u003e\n\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eActive or historical arterial thromboembolic disease\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e, including recent stroke or myocardial infarction (heart attack). \u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-list: l4 level1 lfo6; tab-stops: list 36.0pt;\"\u003e\n\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eSevere liver disease\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e or liver impairment where baseline liver function tests have not returned to normal. \u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-list: l4 level1 lfo6; tab-stops: list 36.0pt;\"\u003e\n\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003ePregnancy or breastfeeding\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e (this medication is strictly contraindicated for pregnant individuals).\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; margin-left: 36.0pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"MsoNormal\" align=\"center\" style=\"margin-bottom: .0001pt; text-align: center; line-height: normal;\"\u003e\u003chr size=\"2\" width=\"100%\" align=\"center\"\u003e\u003c\/div\u003e\n\u003cp class=\"MsoNormal\" style=\"mso-margin-top-alt: auto; mso-margin-bottom-alt: auto; line-height: normal; mso-outline-level: 3;\"\u003e\u003cb\u003e\u003cspan style=\"font-size: 13.5pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eFrequently Asked Questions (FAQs)\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eHow long can I expect to stay on Activelle (1+0.5)mg?\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e\u003cbr\u003eThe duration of HRT therapy is highly individualized. Your healthcare professional will re-evaluate your symptoms at least once a year to determine if you still require treatment or if the dose can be tapered down safely.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eWhat should I do if my vaginal bleeding persists after 6 months?\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e\u003cbr\u003eWhile minor spotting is perfectly normal during the initial months of a continuous combined HRT cycle, any bleeding that begins \u003ci\u003eafter\u003c\/i\u003e the first 6 months, or continues after you stop taking the medicine, must be evaluated promptly by your doctor to rule out changes to the uterine lining.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cb\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003eWill Activelle prevent pregnancy?\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e\u003cbr\u003eNo. \u003cb\u003eActivelle is not an oral contraceptive pill\u003c\/b\u003e. It is a hormone replacement therapy for women who are already postmenopausal. If you are in the perimenopausal transition and still require birth control, speak to your doctor about appropriate options.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e\u003cspan style=\"font-size: 12.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman';\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: .0001pt; line-height: normal;\"\u003e \u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e \u003c\/p\u003e","brand":"Reliable Rx Pharmacy","offers":[{"title":"Default Title","offer_id":67688920416323,"sku":"386","price":12.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/4181\/7155\/files\/NoImage_7ed7ccd2-ca11-4767-964c-425e67ce5e17.jpg?v=1792572496","url":"https:\/\/www.reliablerxpharmacy.co.uk\/products\/activelle-1-0-5mg","provider":"Reliable Rx Pharmacy","version":"1.0","type":"link"}